Typhoid Vaccine

Class 2 Drug Alert (Action Within 48 hours): Sanofi Pasteur MSD Limited - Typhim Vi - Typhoid Polysaccharide Vaccine - EL (12)A/33

The MHRA today issued a drug alert to healthcare professionals advising them that
the manufacturer Sanofi Pasteur MSD has recalled 16 batches of their typhoid
vaccine, Typhim Vi.

he Medicines and Healthcare products Regulatory Agency (MHRA) today issued a drug alert to healthcare professionals advising them that the manufacturer Sanofi Pasteur MSD has recalled 16 batches of their typhoid vaccine, Typhim Vi.

This recall is due to concerns about the effectiveness of the vaccine in some syringes distributed from 7 January 2011 following filling problems in the manufacturing process. Therefore some patients who have been vaccinated with Typhim Vi may not be fully protected against the disease.

If you received this vaccine and have recently returned from abroad, and are unwell, you should contact your doctor.

Vaccine is still available and the Department of Health is working with manufacturers to help ensure that current supply problems are resolved as soon as possible.

MHRA Head of Defective Medicines Report Centre, Ian Holloway said: “There are no concerns over the safety of this vaccine but the recall has taken place because the vaccine may not be as effective as it should be.

“Anyone who has been to a typhoid region of the world and has a fever, abdominal pain and vomiting should contact a healthcare professional. They can also give them information and advice about minimising the risk of getting typhoid.”

Typhim Vi batches being recalled are in this document:
http://www.mhra.gov.uk/home/groups/is-md/documents/websiteresources/con192144.pdf

For medical information enquiries, please telephone  0800 7311654 or fax to 01628 635072.

Evotrox Oral Solution 25, 250, 100mcg per 5ml

Class 2 Drug Alert (Action Required Within 48 Hours): Evotrox 25, 50 and 100 micrograms/5ml Oral Solution by Kappin Limited - EL (12) A/27

Kappin Limited is recalling all remaining stock of the above products because variable stability data do not give an assurance of the product product quality. Recipients of this Drug Alert should bring it to the attention of relevant contacts by copy of this letter. Primary care trusts are asked to forward this to relevant clinics and to general practioners and community pharmacists for information.

Zovirax Suspension 200mg/5ml

Class 2 Drug Alert (Action Within 48 hours): Zovirax Suspension 200mg/5ml - GlaxoSmithKline UK - EL (12) A/25

GlaxoSmithKline UK are recalling multiple batches of 125ml bottles of the above product. This is due to incorrect dosing instructions on the Patient Information Leaflet advising patients to take half the recommended dose.

Class 2 Drug Alert for Paracetamol 500mg Tablets

Class 2 Drug Alert (Action Within 48 Hours) Paracetamol Tablets 500mg  - Actavis UK Ltd

Actavis UK Ltd are recalling all remaining packed stocks of 500mg Paracetamol Tablets to wholesaler, Pharmacy and Clinic level. This is due to the use of incorrect blister foil which fails to meet the specification for child resistance.