Class 2 Drug Alert (Action Within 48 hours): Sanofi Pasteur MSD Limited - Typhim Vi - Typhoid Polysaccharide Vaccine - EL (12)A/33
The MHRA today issued a drug alert to healthcare professionals advising them that
the manufacturer Sanofi Pasteur MSD has recalled 16 batches of their typhoid
vaccine, Typhim Vi.
he Medicines and Healthcare products Regulatory Agency (MHRA) today issued a drug alert to healthcare professionals advising them that the manufacturer Sanofi Pasteur MSD has recalled 16 batches of their typhoid vaccine, Typhim Vi.
This recall is due to concerns about the effectiveness of the vaccine in some syringes distributed from 7 January 2011 following filling problems in the manufacturing process. Therefore some patients who have been vaccinated with Typhim Vi may not be fully protected against the disease.
If you received this vaccine and have recently returned from abroad, and are unwell, you should contact your doctor.
Vaccine is still available and the Department of Health is working with manufacturers to help ensure that current supply problems are resolved as soon as possible.
MHRA Head of Defective Medicines Report Centre, Ian Holloway said: “There are no concerns over the safety of this vaccine but the recall has taken place because the vaccine may not be as effective as it should be.
“Anyone who has been to a typhoid region of the world and has a fever, abdominal pain and vomiting should contact a healthcare professional. They can also give them information and advice about minimising the risk of getting typhoid.”
Typhim Vi batches being recalled are in this document:
http://www.mhra.gov.uk/home/groups/is-md/documents/websiteresources/con192144.pdf
For medical information enquiries, please telephone 
0800 7311654 or fax to 01628 635072.
